CLINICAL HISTORY

95 years old Female "fall from toilet, unclearmedications or medical history, actually with confusion, right flank/rib pain,abdominal distention.

IMAGING FINDINGS

Extensive dense symmetric calcifications throughout the bilateral globus pallidus, dentate nuclei, red nuclei, deep cerebralperiventricular and supraventricular white matter, deep cerebellarwhite matter, and posterior limb internal capsules.

IMAGES

DISCUSSION

Fahr’s disease (or bilateral striopallidodentate calcinosis) is a rare neurodegenerative disorder of unknown cause characterised by symmetrical calcium deposition in the brain; it can be sporadic or autosomal dominant1
The German pathologist Karl Theodor Fahr first described it in 1930.2

Patients most commonly present with movement disorders. In addition, cognitive impairment, seizures, cerebellar signs and dysarthria can be seen 3
is characterized by the bilaterally symmetric deposition of calcium (and other
minerals) in the basal ganglia, thalamus, dentate  nuclei, and centrum semiovale in the absence of
hypoparathyroidism. The Globos pallidus is the most common site of Ca.
At neuroimaging, the condition is characterized by bilaterally symmetric dense calcifications in the basal ganglia, dentate nuclei, thalamus, and subcortical white matter of the cerebrum